Monosodium Urate (Gout)
Needle-like crystals that can be seen in synovial fluids of patients with gout.
Can be differentiated from pseudogout with a polarizing microscope. Monosodium Urate crystals are yellow when parallel to the axis and blue when perpendicular, opposite of calcium pyrophosphate.
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Calcium Pyrophosphate (Pseudo-Gout)
Typically small rhomboid, square, or rodlike crystals. Can be seen in synovial fluid of patients with pseudogout.
Can be differentiated from true gout with a polarizing microscope. Calcium pyrophosphate is blue when parallel to the axis and yellow when perpendicular, opposite of monosodium urate crystals.
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Cholesterol
Can be differentiated from true gout with a polarizing microscope. Calcium pyrophosphate is blue when parallel to the axis and yellow when perpendicular, opposite of monosodium urate crystals.
Can be seen in pleural fluids in patients with inflammatory disorders like rheumatoid arthritis.
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