Cytoplasm contains one or more blue/gray inclusions, usually along the periphery. May be accompanied with toxic granulation or vacuolization.

Seen most often in infection.

Cytoplasm contains coarse, dark blue granules. May be accompanied with dohle bodies or vacuolization.

Seen most often in infection.

Cytoplasm contains vacuoles, indicating phagocytosis. May be accompanied by dohle bodies or toxic granulation.

Seen most often in infection or inflammation. Can also be seen as a result of cell degradation.

AKA “Green Crystals of Death” due to being associated with poor prognosis.

Bright green/blue refractile inclusions in the cytoplasm.

Rare finding typically seen in critically ill patients.

Nucleus is hyposegmented, either bilobed or monolobed. Bilobed neutrophils are described as having a characteristic pince-nez shape (a particular style of glasses). Monolobed neutrophils may be mistaken as myelocytes if care is not taken. However, chromatin is notably condensed upon closer inspection

True Pelger-Huet neutrophils are an inherited disorder and completely benign. The majority of neutrophils will be hyposegmented.

Pseudo-Pelger-Huet, or pelgeroid cells, can be caused by certain medications or Myelodysplastic Syndromes.

Nucleus has 6 or more lobes. Cell is usually larger than normal neutrophils.

Can be hereditary. Also seen in Megaloblastic hematopoiesis due to nutritional deficiencies.

Degenerated neutrophil. Nucleus stains densely blue or purple. Filament between lobes may no longer be visible.

Can be seen normally in blood smear.