White blood cell casts usually accompanied by more white blood cells in the urine and positive leukocyte esterase on the urine chemistries.
These casts indicate renal inflammation or renal infection.
Appearance
White blood cells (mostly polymorphonuclear neutrophils) can be seen in a protein matrix. Some of these cells may be partially broken down into granules.

Lookalikes
White blood cell clumps may be mistaken for white blood cell casts. However, they will have irregular edges and no visible protein matrix.
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