Calcium Phosphate Crystals are found in alkaline or neutral urine. They are soluble in dilute acetic acid.
These crystals may be found in normal urine but may also form renal calculi.
Wedge / Needle
Calcium Phosphate crystals typically appear as thin, wedge-like rods with variable birefringence

Rosette
These rods can also form in star-like clusters with variable birefringence.

Plates
The crystals may also appear as large, irregular plates that may form a scum on the surface of sitting urine. These plates show no birefringence.
Lookalikes
Bilirubin crystals can look similar to calcium phosphate rosettes when they form in clusters. However, bilirubin crystals are easily identified by the presence of bilirubin which typically stains other elements. They are also found in acidic, not alkaline urine.
Tyrosine crystals form in both needles and clusters. However, tyrosine needles are much more fine than the wedge-like calcium phosphate. Tyrosine crystals are sometimes described as “hair-like.”
Tyrosine Crystals

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Other Crystals
Hippuric Acid

Tyrosine










