Myelocytes are not normally found in peripheral blood. Their presence indicates infection when seen with other immature neutrophils. Increased amounts of these cells can also be seen in conditions like chronic myeloid leukemia (CML). This is also the last neutrophil stage capable of cell division.
Myelocyte Appearance
Myelocytes have a pinkish blue cytoplasm with both azurophilic (primary) and specific (secondary) granules. The nucleus is usually eccentrically placed and may appear flattened on one side. Nucleoli are usually not visible, and chromatin is fine with some clumping.
Lookalikes
Myelocytes can be differentiated from promyelocytes by the presence of the pinkish secondary granules. Primary azurophilic granules are present in both cells.
Myelocyte Gallery
